1. Braswell S.F., Kostopoulos T.C., Ortega-Loayza A.G. Pathophysiology of pyoderma gangrenosum (PG): an updated review. J Am Acad Dermatol. 2015; 73 (4): 691 - 698.

2. Alavi A., French L.E., Davis M.D. et al. Pyoderma gangrenosum: an update on pathophysiology, diagnosis and treatment. Am J Clin Dermatol. 2017; 18 (3): 355 - 372.

3. Fletcher J., Alhusayen R., Alavi A. Recent advances in managing and understanding pyoderma gangrenosum. F1000Research 2019, 8 (F1000 Faculty Rev): 2092.

4. Mittal S., Milner B.J., Vickers M.A. Pyoderma gangrenosum as a cause of splenomegaly and association with a T-cell clone. Clin Lab Haematol. 2005; 27 (6): 402 - 404.

5. Brooklyn T.N., Williams A.M., Dunnill M.G., Probert C.S. T-cell receptor repertoire in pyoderma gangrenosum: evidence for clonal expansions and trafficking. Br J Dermatol. 2007; 157 (5): 960 - 966.

6. Patel F., Fitzmaurice S., Duong C. et al. Effective strategies for the management of pyoderma gangrenosum: a comprehensive review. Acta Derm Venerol. 2015; 95 (5): 525 - 531.

7. Tanaka N., Fujioka A., Tajima S. et al. Elafin is induced in epidermis in skin disorders with dermal neutrophilic infiltration: interleukin-1 beta and tumour necrosis factor-alpha stimulate its secretion in vitro. Br J Dermatol. 2000; 143 (4): 728 - 732.

8. Marzano A.V., Cugno M., Trevisan V. et al. Role of inflammatory cells, cytokines and matrix metalloproteinases in neutrophil-mediated skin diseases. Clin Exp Immunol. 2010; 162 (1): 100 - 107.

9. McKenzie F., Cash D., Gupta A. Biologic and small-molecule medications in the management of pyoderma gangrenosum. J Dermatolog Treat. 2019; 30 (3): 264 - 276.

10. Marzano A.V., Fanoni D., Antiga E. et al. Expression of cytokines, chemokines and other effector molecules in two prototypic autoinflammatory skin diseases, pyoderma gangrenosum and Sweet's syndrome. Clin Exp Immunol. 2014; 178 (1): 48 - 56.

11. Marzano A.V., Damiani G., Ceccherini I. et al. Autoinflammation in pyoderma gangrenosum and its syndromic form (pyoderma gangrenosum, acne and suppurative hidradenitis). Br J Dermatol. 2017; 176 (6): 1588 - 1598.

12. Kolios A.G., Maul J.T., Meier B. et al.: Canakinumab in adults with steroid-refractory pyoderma gangrenosum. Br J Dermatol. 2015; 173 (5): 1216 - 1223.

13. Wang E.A., Steel A., Luxardi G. et al. Classic ulcerative pyoderma gangrenosum is a T cell-mediated disease targeting follicular adnexal structures: a hypothesis based on molecular and clinicopathologic studies. Front Immunol. 2018; 8: 1980.

14. Guenova E., Teske A., Fehrenbacher B. et al. Interleukin 23 expression in pyoderma gangrenosum and targeted therapy with ustekinumab. Arch Dermatol. 2011; 147 (10): 1203 - 1205.

15. Caproni M., Antiga E., Volpi W. et al. The Treg/Th17 cell ratio is reduced in the skin lesions of patients with pyoderma gangrenosum. Br J Dermatol. 2015; 173 (1): 275 - 278.

16. Ortega-Loayza A.G., Nugent W.H., Lucero O.M. et al. Dysregulation of inflammatory gene expression in lesional and nonlesional skin of patients with pyoderma gangrenosum. Br J Dermatol. 2018; 178 (1): e35 - e36.

17. Alves de Medeiros A.K., Speeckaert R., Desmet E. et al. JAK3 as an emerging target for topical treatment of inflammatory skin diseases. PLoS One. 2016; 11 (10): e0164080.

18. Gameiro A., Pereira N., Cardoso J.C., Gon alo M. Pyoderma gangrenosum: challenges and solutions. Clin Cosmet Investig Dermatol 2015; 8: 285 - 293.

19. Alavi A., Sajic D., Cerci F.B. et al. Neutrophilic dermatoses: an update. Am J Clin Dermatol. 2014; 15 (5): 413 - 423.

20. DeFilippis E.M., Feldman S.R., Huang W.W. The genetics of pyoderma gangrenosum and implications for treatment: A systematic review. Br J Dermatol. 2015; 172 (6): 1487 - 1497.

21. Bruzzese V. Pyoderma gangrenosum, acne conglobata, suppurative hidradenitis, and axial spondyloarthritis: efficacy of anti-tumor necrosis factor therapy. J Clin Rheumatol. 2012; 18 (8): 413 - 415.

22. Duchatelet S., Miskinyte S., Join-Lambert O. et al. First nicastrin mutation in PASH (pyoderma gangrenosum, acne and suppurative hidradenitis) syndrome. Br J Dermatol. 2015; 173 (2): 610 - 612.

23. Khandpur S., Mehta S., Reddy B.S. Pyoderma gangrenosum in two siblings: a familial predisposition. Pediatr Dermatol. 2001; 18 (4): 308 - 312.

24. Boussofara L., Gammoudi R., Ghariani N. Familial pyoderma gangrenosum in association with common variable immunodeficiency. Br J Dermatol. 2013; 169 (4): 944 - 946.

25. al-Rimawi H.S., Abuekteish F.M., Daoud A.S. et al. Familial pyoderma gangrenosum presenting in infancy. Eur J Pediatr. 1996; 155 (9): 759 - 762.

26. Shands J.W. Jr, Flowers F.P., Hill H.M. et al. Pyoderma gangrenosum in a kindred. Precipitation by surgery or mild physical trauma. J Am Acad Dermatol. 1987; 16 (5 Pt 1): 931 - 934.

27. Maggio M.C., Ceccherini I., Grossi A. et al.: PAPA and FMF in two siblings: Possible amplification of clinical presentation? A case report. Ital J Pediatr. 2019; 45 (1): 111.

28. Wollina U. Pyoderma gangrenosum - a review. Orphanet J Rare Dis. 2007; 2: 19.

29. Ruocco E., Sangiuliano S., Gravina A.G. et al. Pyoderma gangrenosum: an updated review. J Eur Acad Dermatol Venereol. 2009; 23 (9): 1008 - 1017.

30. Langan S.M., Groves R.W., Card T.R. et al. Incidence, mortality, and disease associations of pyoderma gangrenosum in the United Kingdom: a retrospective cohort study. J Invest Dermatol. 2012. 132 (9): 2166 - 2170.

31. Ashchyan H.J., Butler D.C., Nelson C.A. et al. The association of age with clinical presentation and comorbidities of pyoderma gangrenosum. JAMA Dermatol. 2018; 154 (4): 409 - 413.

32. Xu A., Balgobind A., Strunk A. et al. Prevalence estimates for pyoderma gangrenosum in the United States: An age- and sex-adjusted population analysis. J Am Acad Dermatol. 2020; 83 (2): 425 - 429.

33. Pereira N., Brites M.M., et al. Pyoderma gangrenosum - a review of 24 cases observed over 10 years. Int J Dermatol. 2013; 52 (8): 938 - 945.

34. Dasanu C.A., Bockorny B., Alexandrescu D.T. Pyoderma gangrenosum due to lenalidomide use for multiple myeloma. J Oncol Pharm Pract. 2015; 21 (6): 471 - 473.

35. Duchnowska R., Ziajka E., , Grala B. Recurrent pyoderma gangrenosum precipitated by breast cancer: a case report and review of the literature. J Med Case Rep. 2014; 8: 226.

36. Binus A.M., Qureshi A.A., Li V.W., Winterfield L.S. et al. Pyoderma gangrenosum: a retrospective review of patient characteristics, comorbidities and therapy in 103 patients. Br J Dermatol. 2011; 165 (6): 1244 - 1250.

37. Powell F.C., Su W.P., Perry H.O. Pyoderma gangrenosum: classification and management. J Am Acad Dermatol. 1996; 34 (3): 395 - 409; quiz 410 - 412.

38. , Pyoderma Gangrenosum. J Turk Acad Dermatol. 2007; 1 (3): 71301r.

39. Feliciani C., De Simone C., Amerio P. Dermatological signs during inflammatory bowel diseases. Eur Rev Med Pharmacol Sci. 2009; 13 Suppl 1: 15 - 21.

40. Vidal D., Puig L., Gilaberte M. et al. Review of 26 cases of classical pyoderma gangrenosum: clinical and therapeutic features. J Dermatolog Treat. 2004; 15 (3): 146 - 152.

41. Su W.P., Davis M.D., Weenig R.H. et al. Pyoderma gangrenosum: clinicopathologic correlation and proposed diagnostic criteria. Int J Dermatol. 2004; 43 (11): 790 - 800.

42. Landis E.T., Taheri A., Jorizzo J.L. Gulliver's sign: a recognizable transition from inflammatory to healing stages of pyoderma gangrenosum. J Dermatolog Treat. 2015; 26 (2): 171 - 172.

43. Von den Driesch P. Pyoderma gangrenosum: a report of 44 cases with follow-up. Br J Dermatol. 1997; 137 (6): 1000 - 1005.

44. Powell F.C., Schroeter A.L., Su W.P. et al. Pyoderma gangrenosum: a review of 86 patients. Q J Med. 1985 May; 55 (217): 173 - 186.

45. Powell F.C., Perry H.O. Pyoderma gangrenosum in childhood. Arch Dermatol. 1984; 120 (6): 757 - 761.

46. Chia M.W., Teo L., Tay Y.K., Poh W.T. Pustular pyoderma gangrenosum: an uncommon variant which is easily misdiagnosed. Dermatol Online J. 2008; 14: 21.

47. O'Loughlin S., Perry H.O. A diffuse pustular eruption associated with ulcerative colitis. Arch Dermatol. 1978; 114 (7): 1061 - 1064.

48. Omiya W., Ujiie H., Akiyama M. et al. Coexistence of pustular and vegetative pyoderma gangrenosum in a patient with myelodysplastic syndrome. Eur J Dermatol. 2012; 22 (5): 711 - 712.

49. Speeckaert R., De Smet L., De Schepper S. et al. Pyoderma gangrenosum with granuloma formation: not always a benign disorder. J Eur Acad Dermatol Venereol. 2016; 30 (1): 188 - 189.

50. Xia F.D., Liu K., Lockwood S. et al. Risk of developing pyoderma gangrenosum after procedures in patients with a known history of pyoderma gangrenosum-A retrospective analysis. J Am Acad Dermatol. 2018; 78 (2): 310 - 314.

51. Hughes A.P., Jackson J.M., Callen J.P. Clinical features and treatment of peristomal pyoderma gangrenosum. JAMA. 2000; 284 (12): 1546 - 1548.

52. Wu X.R., Shen B. Diagnosis and management of parastomal pyoderma gangrenosum. Gastroenterol Rep (Oxf). 2013; 1 (1): 1 - 8.

53. Reichrath J., Bens G., Bonowitz A., Tilgen W. Treatment recommendations for pyoderma gangrenosum: an evidence-based review of the literature based on more than 350 patients. J Am Acad Dermatol. 2005; 53 (2): 273 - 283.

54. Gade M., Studstrup F., Andersen A.K. et al. Pulmonary manifestations of pyoderma gangrenosum: 2 cases and a review of the literature. Respir Med. 2015; 109 (4): 443 - 450.

55. Ahronowitz I., Harp J., Shinkai K. Etiology and management of pyoderma gangrenosum: a comprehensive review. Am J Clin Dermatol. 2012; 13 (3): 191 - 211.

56. , Piroth W., Amo Takyi B. et al. Multiple aseptic pulmonary nodules with central necrosis in association with pyoderma gangrenosum. Chest. 2001; 119: 977 - 978.

57. Miserocchi E., Modorati G., Foster C.S., Brancato R. Ocular and extracutaneous involvement in pyoderma gangrenosum. Opthalmology. 2002; 109: 1941 - 1943.

58. Vignon-Pennamen M.D. The extracutaneous involvement in the neutrophillic dermatoses. Clin Dermatol. 2000; 18: 339 - 347.

59. Marie I., Levesque H., Joly P. et al. Neutrophilic myositis as an extracutaneous manifestation of neutrophilic dermatosis. J Am Acad Dermatol. 2001; 44 (1): 137 - 139.

60. Be M., Cha H.J., Park C. et al. Multiple cavitary nodules with pyoderma gangrenosum in patients with rheumatoid arthritis. Ann Transl Med. 2016; 4: 39.

61. Nguyen K.H., Miller J.J., Helm K.F. Case reports and a review of the literature on ulcers mimicking pyoderma gangrenosum. Int J Dermatol. 2003; 42 (2): 84 - 94.

62. , , Fonte-Avalos V. et al. The great imitator with no diagnostic test: pyoderma gangrenosum. Int Wound J. 2020; 17 (6): 1774 - 1782.

63. Su W.P., Schroeter A.L., Perry H.O. et al. Histopathologic and immunopathologic study of pyoderma gangrenosum. J Cutan Pathol. 1986; 13 (5): 323 - 330.

64. Maverakis E., Ma C., Shinkai K. et al. Diagnostic criteria of ulcerative pyoderma gangrenosum: a Delphi Consensus of International Experts. JAMA Dermatol. 2018; 154 (4): 461 - 466.

65. Bennett M.L., Jackson J.M., Jorizzo J.L. et al. Pyoderma gangrenosum: a comparison of typical and atypical forms with an emphasis on time to remission. Case review of 86 patients from 2 institutions. Medicine (Baltimore). 2000; 79 (1): 37 - 46.

66. Weenig R.H., Davis M.D., Dahl P.R. et al. Skin ulcers misdiagnosed as pyoderma gangrenosum. N Engl J Med. 2002; 347 (18): 1412 - 1418.

67. Goodarzi H., Sivamani R.K., Garcia M.S. et al. Effective strategies for the management of pyoderma gangrenosum. Adv Wound Care. 2012; 1 (5): 194 - 199.

68. Wolverton S.E. Monitoring for adverse effects from systemic drugs used in dermatology. J Am Acad Dermatol. 1992; 26: 661 - 679.

69. Molinelli E., Paolinelli M., Campanati A. et al. Metabolic, pharmacokinetic, and toxicological issues surrounding dapsone. Expert Opin Drug Metab Toxicol. 2019; 15 (5): 367 - 379.

70. Ryan C., Amor K.T., Menter A. The use of cyclosporine in dermatology: part II. J Am Acad Dermatol. 2010; 63 (6): 949 - 972.

71. Zhu Y.I., Stiller M.J. Dapsone and sulphones in dermatology: Overview and update. J Am Acad Dermatol. 2001; 45 (3): 420 - 434.

72. Bessissow T., Renard M., Hoffman I. et al. Review article: non-malignant haematological complications of anti-tumour necrosis factor alpha therapy. Aliment Pharmacol Ther. 2012; 36 (4): 312 - 323.

73. Kellen R., Silverberg N.B., Lebwohl M. Pediatric Health Med Ther. Efficacy and safety of ustekinumab in adolescents. 2016; 7: 109 - 120.

74. Summary of product characteristics. Электронный ресурс. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/001109/WC500031680.pdf Дата доступа: 21-ЯНВ-2021.

75. Conway R., Low C., Coughlan R.J. et al. Risk of liver injury among methotrexate users: A meta-analysis of randomised controlled trials. Semin Arthritis Rheum. 2015; 45 (2): 156 - 162.

76. Rossi R.E., Parisi I., Despott E.J. et al. Anti-tumour necrosis factor agent and liver injury: literature review, recommendations for management. World J Gastroenterol. 2014; 20 (46): 17352 - 17359.

77. Kok B., Lester E.L., Lee W.M. et al. Acute liver failure from tumor necrosis factor-antagonists: Report of four cases and literature review. Dig Dis Sci. 2018; 63 (6): 1654 - 1666.

78. Shah P., Sundaram V., Bj rnsson E. Biologic and checkpoint inhibitor-induced liver injury: A systematic literature review. Hepatol Commun. 2020; 4 (2): 172 - 184.

79. French J.B., Bonacini M., Ghabril M. et al. Hepatotoxicity associated with the use of anti-TNF-agents. Drug Saf. 2016; 39 (3): 199 - 208.

80. Ghabril M., Bonkovsky H.L., Kum C. et al. Liver injury from tumor necrosis factor-antagonists: Analysis of thirty-four cases. Clin Gastoenterol Hepatol. 2013; 11 (5): 558 - 564. e3.

81. , Gunnarsson B.I., et al. Risk of drug-induced liver injury from tumor necrosis factor antagonists. Clin Gastoenterol Hepatol. 2015; 13 (3): 602 - 608.

82. , Torre-Cisneros J., et al. Infections in patients treated with tumor necrosis factor antagonists: incidence, etiology and mortality in the BIOBADASER registry. Med Clin (Barc). 2011; 137 (12): 533 - 540.

83. Burmester G.R., Gordon K.B., Rosenbaum J.T. et al. Long-term safety of adalimumab in 29,967 adult patients from global clinical trials across multiple indications: An updated analysis. Adv Ther. 2020; 37 (1): 364 - 380.

84. Powell F.C., Schroeter A.L., Perry H.O. et al. Direct immunofluorescence in pyoderma gangrenosum. Br J Dermatol. 1983; 108: 287 - 293.

85. Godfrey M.S., Friedman L.N. Tuberculosis and biologic therapies: Anti-tumor necrosis factor- and beyond. Clin Chest Med. 2019; 40 (4): 721 - 739.

86. Lalvani A., Millington K.A. Screening for tuberculosis infection prior to initiation of anti-TNF therapy. Autoimmun Rev. 2008; 8 (2): 147 - 152.

87. Bellini V., Simonetti S., Lisi P. Successful treatment of severe pyoderma gangrenosum with pimecrolimus cream 1%. J Eur Acad Dermatol Venereol. 2008; 22 (1): 113 - 115.

88. Dillingham C.S., Jorizzo J. Managing ulcers associated with pyoderma gangrenosum with a urinary bladder matrix and negative-pressure wound therapy. Adv Skin Wound Care. 2019; 32 (2): 70 - 76.

89. Goldust M., Hagstrom E.L., Rathod D., Ortega-Loayza A.G. Diagnosis and novel clinical treatment strategies for pyoderma gangrenosum. Expert Rev Clin Pharmacol. 2020; 13 (2): 157 - 161.

90. Slocum A.M. A surgeon's nightmare: pyoderma gangrenosum with pathergy effect mimicking necrotising fasciitis. BMJ Case Rep. 2017; 2017: bcr2017222145.

91. Sakai H., Otsubo S., Iizuka H. Peristomal pyoderma gangrenosum associated with rectal adenocarcinoma. J Dermatol. 2006; 33 (1): 68 - 70.

92. Miyata T., Yashiro M., Hayashi M. et al. Bullous pyoderma gangrenosum of the bilateral dorsal hands. J Dermatol. 2012; 39 (12): 1006 - 1009.

93. Castillo R.F., Ca adas-De la Fuente G.A., Husein-Elahmed H., Cantero-Hinojosa J. Pyoderma gangrenosum developing over an arteriovenous fistula scar. Intern Med J. 2011; 41 (5): 436 - 437.

94. Thomas K.S., Ormerod A.D., Craig F.E. et al. Clinical outcomes and response of patients applying topical therapy for pyoderma gangrenosum: A prospective cohort study. J Am Acad Dermatol. 2016; 75 (5): 940 - 949.

95. Abdelrahman W., Walsh M.Y., Hoey S.E., O'Kane D. Pyoderma gangrenosum: A rare cause of cutaneous ulceration and one easily misdiagnosed. Case Rep Pediatr. 2016; 2016: 5971706.

96. Marzano A.V., Trevisan V., Lazzari R., Crosti C. Pyoderma gangrenosum: study of 21 patients and proposal of a 'clinicotherapeutic' classification. J Dermatolog Treat. 2011; 22 (5): 254 - 260.

97. Altieri M., Vaziri K., Orkin B.A. Topical tacrolimus for parastomal pyoderma gangrenosum: a report of two cases. Ostomy Wound Manage. 2010; 56 (9): 56 - 59.

98. Chiba T., Isomura I., Suzuki A., Morita A. Topical tacrolimus therapy for pyoderma gangrenosum. J Dermatol. 2005; 32 (3): 199 - 203.

99. Petering H., Kiehl P.,· Breuer C. et al. Pyoderma gangraenosum: Erfolgreiche topische Therapie mit Tacrolimus (FK506). Hautarzt. 2001; 52 (1): 47 - 50.

100. Gettler S.L., Rothe M.J., Grin C., Grant-Kels J.M. Optimal treatment of pyoderma gangrenosum. Am J Clin Dermatol. 2003; 4 (9): 597 - 608.

101. Johnson R.B., Lazarus G.S. Pulse therapy: therapeutic efficacy in the treatment of pyoderma gangrenosum. Arch Dermatol 1982; 118: 76 - 84.

102. Prystowsky J.H., Kahn S.N., Lazarus G.S. Present status of pyoderma gangrenosum: review of 21 cases. Arch Dermatol. 1989; 125 (1): 57 - 64.

103. Yamauchi T., Ishida K., Iwashima Y. et al. Successful treatment of pyoderma gangrenosum that developed in a patient with myelodysplastic syndrome. J Infect Chemother. 2003; 9 (3): 268 - 271.

104. Ogata K., Takamori H., Ikuta Y. et al. Pyoderma gangrenosum in an abdominal surgical site: a case report. Surg Case Rep. 2015; 1 (1): 122.

105. Ormerod A.D., Thomas K.S., Craig F.E. et al. Comparison of the two most commonly used treatments for pyoderma gangrenosum: results of the STOP GAP randomised controlled trial. BMJ. 2015; 350: h2958.

106. Jain A.G., Sharbatji M., Afzal A. et al. Pyoderma gangrenosum in the absence of any underlying predisposing condition: A diagnostic dilemma. Cureus. 2019; 11 (3): e4213.

107. Уфимцева М.А., Бочкарев Ю.М., Чернядьев С.А. и др. Гангренозная пиодермия - междисциплинарная проблема. Вестник хирургии имени И.И. Грекова. 2020; 179 (3): 95 - 99.

108. Hasselmann D.O., Bens G., Tilgen W., Reichrath J. Pyoderma gangrenosum: clinical presentation and outcome in 18 cases and review of the literature. J Dtsch Dermatol Ges. 2007; 5 (7): 560 - 564.

109. Soria C., Allegue F., Martin M., Ledo A. Treatment of pyoderma gangrenosum with cyclosporin A. Clin Exp Dermatol. 1991; 16 (5): 392 - 394.

110. Matis W.L., Ellis C.N., Griffiths C.E., Lazarus G.S. Treatment of pyoderma gangrenosum with cyclosporine. Arch Dermatol. 1992; 128 (8): 1060 - 1064.

111. Busick T.L., Bennett D.D., Cohen J.B. Pyoderma gangrenosum responding to ciclosporin without adverse effects in a patient with lymphomatoid papulosis. Clin Exp Dermatol. 2010; 35 (8): 918 - 919.

112. Anwar S., Holfeld K., Prasad B. Peritoneal dialysis exit site pyoderma gangrenosum: A case report. Case Rep Nephrol Dial. 2018; 8 (3): 239 - 245.

113. Brown R.E., Lay L., Graham D. Bilateral pyoderma gangrenosum of the hand: treatment with dapsone. J Hand Surg Br. 1993; 18 (1): 119 - 121.

114. Fukuhara K., Urano Y., Kimura S. et al. Pyoderma gangrenosum with rheumatoid arthritis and pulmonary aseptic abscess responding to treatment with dapsone. Br J Dermatol. 1998; 139 (3): 556 - 558.

115. Eaton P.A., Callen J.P. Mycophenolate mofetil as therapy for pyoderma gangrenosum. Arch Dermatol. 2009; 145 (7): 781 - 785.

116. Roche L., Gulman C., O'Kane M. A case of genital pyoderma gangrenosum successfully treated with cyclosporine without relapse of established follicular lymphoma. JAAD Case Rep. 2018; 4 (5): 474 - 476.

117. Ndahi A.A., Tahir C., Nggada H.A. Photoletter to the editor: Scarring alopecia resulting from pyoderma gangrenosum of the scalp. J Dermatol Case Rep. 2012; 6 (1): 34 - 35.

118. Brooklyn T.N., Dunnill M.G., Shetty A. et al. Infliximab for the treatment of pyoderma gangrenosum: a randomised, double blind, placebo controlled trial. Gut. 2006; 55 (4): 505 - 509.

119. Ferkolj I., Hocevar A., Golouh R., Dolenc Voljc M. Infliximab for treatment of resistant pyoderma gangrenosum associated with Crohn's disease. Acta Dermatovenerol Alp Pannonica Adriat. 2006; 15 (4): 173 - 177.

120. Marzano A.V., Tourlaki A., Alessi E., Caputo R. Widespread idiopathic pyoderma gangrenosum evolved from ulcerative to vegetative type: a 10-year history with a recent response to infliximab. Clin Exp Dermatol. 2008; 33 (2): 156 - 159.

121. Zampeli V.A., Lippert U., Nikolakis G. et al. Disseminated refractory pyoderma gangraenosum during an ulcerative colitis flare. Treatment with infliximab. J Dermatol Case Rep. 2015; 9: 62 - 66.

122. Cocco A., Angelucci E., Viscido A., Caprilli R. Successful treatment with infliximab of refractory pyoderma gangrenosum in 2 patients with inflammatory bowel diseases. Inflamm Bowel Dis. 2017; 13 (10): 1317 - 1319.

123. Stichweh D.S., Punaro M., Pascual V. Dramatic improvement of pyoderma gangrenosum with infliximab in a patient with PAPA syndrome. Pediatr Dermatol. 2005; 22 (3): 262 - 265.

124. Heffernan M.P., Anadkat M.J., Smith D.I. Adalimumab treatment for pyoderma gangrenosum. Arch Dermatol. 2007; 143 (3): 306 - 308.

125. Zold E., Nagy A., Devenyi K. et al. Successful use of adalimumab for treating fistulizing Crohn's disease with pyoderma gangrenosum: two birds with one stone. World J Gastroenterol. 2009; 15 (18): 2293 - 2295.

126. Sagami S., Ueno Y., Tanaka S. et al. Successful use of adalimumab for treating pyoderma gangrenosum with ulcerative colitis under corticosteroid-tapering conditions. Intern Med. 2015; 54 (17): 2167 - 2172.

127. Kleinfelder R.E., Hin N., Cubelli S. et al. Multiple facial lesions of recalcitrant pyoderma gangrenosum successfully treated with adalimumab. J Clin Aesthet Dermatol. 2019; 12 (5): 28 - 32.

128. Charles C.A., Leon A., Banta M.R. et al. Etanercept for the treatment of refractory pyoderma gangrenosum: a brief series. Int J Dermatol 2007; 46 (10): 1095 - 1099.

129. Pastor N., Betlloch I., Pascual J.C. et al. Pyoderma gangrenosum treated with anti-TNF alpha therapy (etanercept). Clin Exp Dermatol. 2006; 31 (1): 152 - 153.

130. Roy D.B., Conte E.T., Cohen D.J. The treatment of pyoderma gangrenosum using etanercept. J Am Acad Dermatol. 2006; 54 (3 Suppl 2): S128 - 134.

131. Rogge F.J., Pacifico M., Kang N. Treatment of pyoderma gangrenosum with the anti-TNF-alpha drug - Etanercept. J Plast Reconstr Aesthet Surg. 2008; 61 (4): 431 - 433.

132. Kim F.S., Pandya A.G. The use of etanercept in the treatment of peristomal pyoderma gangrenosum. Clin Exp Dermatol. 2012; 37 (4): 442 - 443.

133. Goldminz A.M., Botto N.C., Gottlieb A.B. Severely recalcitrant pyoderma gangrenosum successfully treated with ustekinumab. J Am Acad Dermatol. 2012; 67 (5): e237 - 238.

134. Kurzeja M., Rudnicka L., Olszewska M. New interleukin-23 pathway inhibitors in dermatology: ustekinumab, briakinumab, and secukinumab. Am J Clin Dermatol. 2011; 12 (2): 113 - 125.

135. Horner B., El-Muttardi N., Mercer D. Pyoderma gangrenosum complicating bilateral breast reduction. Br J Plast Surg. 2004; 57 (7): 679 - 681.

136. Седов В.М., Андреев Д.Ю., Парамонов Б.А. и др. "Гангренозная пиодермия" как хирургическая проблема. Вестник хирургии имени И.И. Грекова. 2010; 169 (3): 111 - 116.

137. Powell F.C., O'Kane M. Management of pyoderma gangrenosum. Dermatol Clin. 2002; 20 (2): 347 - 355.

138. Барышников Е.Н., Нейман К.П. Гангренозная пиодермия при болезни Крона. Экспериментальная и клиническая гастроэнтерология. 2008; 5: 92 - 94.

139. Габитов С.З. Клинический случай гангренозной пиодермии. Практическая медицина. 2011; 3-1 (50): 47 - 50.

140. Андреев Д.Ю. Аутодермопластика расщепленными лоскутами в лечении гангренозной пиодермии. Вестник хирургии имени И.И. Грекова. 2011; 170 (1): 72 - 75.

141. Кашников В.Н., Михайлова Т.Л., Головенко О.В. и др. Тяжелая генерализованная форма гангренозной пиодермии у больной язвенным колитом (клиническое наблюдение). Колопроктология. 2011; 35 (1): 37 - 40.

142. Патрушев А.В., Самцов А.В., Барбинов В.В. и др. Гангренозная пиодермия: трудности в диагностике и терапии. Вестник дерматологии и венерологии 2014; (1): 25 - 29.

143. Олисова О.Ю., Грабовская О.В., Теплюк Н.П. и др. Новые подходы в лечении язвенных дефектов кожи. Российский журнал кожных и венерических болезней. 2014; 1: 26 - 31.

144. Lynch W.S., Bergfeld W.F. Pyoderma gangrenosum responsive to minocycline hydrochloride. Cutis. 1978; 21 (4): 535 - 538.

145. Davies M.G., Piper S. Pyoderma gangrenosum: successful treatment with minocycline. Clin Exp Dermatol. 1981; 6 (2): 219 - 223.

146. Kandula P., Shah K.M., Wolverton J.E. et al. Pyoderma gangrenosum: a presenting sign of myelodysplastic syndrome in undiagnosed Fanconi anemia. Dermatol Online J. 2019 Jan 15; 25 (1): 13030/qt9xj8b544.

147. Kean J. The effects of smoking on the wound healing process. J Wound Care. 2010; 19 (1): 5 - 8.

148. Nguyen T.V., Cowen E.W., Leslie K.S. Autoinflammation: From monogenic syndromes to common skin diseases. J Am Acad Dermatol. 2013; 68 (5): 834 - 853.

149. Ye M.J., Ye J.M. Pyoderma gangrenosum: a review of clinical features and outcomes of 23 cases requiring inpatient management. Dermatol Res Pract. 2014; 2014: 461467.

150. Batres L.A., Mamula P., Baldassano R.N. Resolution of severe peristomal pyoderma gangrenosum with infliximab in a child with Crohn disease. J Pediatr Gastroenterol Nutr. 2002; 34 (5): 558 - 560.

151. Keskin M., Tosun Z., Ucar C., Savaci N. Pyoderma gangrenosum in a battered child. Ann Plast Surg. 2006; 57 (2): 228 - 230.